Some scientists spot ‘unlikely’ patterns in Russia vaccine data: Letter

first_img“The published results are authentic and accurate and were examined by five reviewers at The Lancet,” Denis Logunov, a deputy director at the institute, said in a statement.He said his institute submitted the entire body of raw data on the trial results to The Lancet.”We presented specifically the data that was produced (by the trial), not the data that is supposed to please Italian experts,” Logunov said.Naor Bar-Zeev, deputy director at John Hopkins Bloomberg School of Public Health, who peer reviewed the Russian data, defended his analysis of the research.”Science must maintain a balance between incredulity, skepticism and trust. That trust is borne out through plausibility, repeatability and falsifiability.””The results are plausible, and not very different to those seen with other AdV vectored products,” he said.The researchers had provided more detail than was needed for the review and responded to his questions “intelligently and in a matter-of-fact and confident but understated manner”.”Bottom line, I saw no reason to doubt the legitimacy of these results over others I have read and reviewed. But of course one can never know,” he said in an email.A spokeswoman for the Lancet said the journal had invited the study’s authors to respond to the questions raised in the open letter. It was following the situation closely, she said.Russia published results on Friday of its Phase I/II trial, which included 76 participants and was conducted in June-July this year. Participants developed a positive immune response and no serious side effects, the study’s authors said.A Phase III trial, involving 40,000 participants, was launched on Aug. 26. Around 31,000 people have already subscribed to take part, Health Minister Mikhail Murashko said. “On the ground of simple probabilistic evaluations the fact of observing so many data points preserved among different experiments is highly unlikely,” the open letter said.However, the scientists said they were basing their conclusions on summaries of the Russian trial result data, published in the journal, rather than the original data itself.”In lack of the original numerical data, no conclusions can be definitively drawn on the reliability of the data presented, especially regarding the apparent duplications detected,” the letter said.The Gamaleya Institute, which developed the vaccine, rejected the critique. Topics :center_img Twenty-six scientists, most of them working at universities in Italy, have signed an open letter questioning the reliability of the data presented in the early-stage trial results of the Russian COVID-19 vaccine, named “Sputnik-V”.Addressing the editor of The Lancet, the international peer-reviewed medical journal in which Moscow’s Gamaleya Institute published its early-stage trial results, the scientists said they saw patterns in the data that looked “highly unlikely”.The letter, published on the personal blog page of one of the signatories, said the Phase I/II trial results data showed multiple participants reporting identical antibody levels.last_img read more

Massachusetts Hospital Association votes to oppose marijuana ballot measure

first_imgBoston Globe 13 March 2016Family First Comment: Listen to the real experts – not advocates for decriminalisation like the Drug Foundation: “The Massachusetts Hospital Association has joined a growing roster of opponents to a proposed ballot measure that would legalize marijuana in Massachusetts.”    The Massachusetts Hospital Association has joined a growing roster of opponents to a proposed ballot measure that would legalize marijuana in Massachusetts.The group’s board of trustees voted unanimously last week to oppose the measure, citing public health and safety concerns, including greater youth access to the drug.“Clinicians and health care leaders from around the state have a clear message — this ballot measure is the wrong prescription for Massachusetts,” said Lynn Nicholas, chief executive of the hospital association, in a written statement.Governor Charlie Baker, Attorney General Maura Healey, and Mayor Martin J. Walsh of Boston recently published a joint opinion article in The Boston Globe reiterating their opposition to the ballot question, which would legalize recreational use of marijuana for those 21 and over.The politicians wrote that where marijuana is legal, young people are more likely to use it. Advocates dispute that.READ MORE: up with family issues in NZ. Receive our weekly emails direct to your Inbox.last_img read more

Africa blasts ICC as world crimes court members meet

first_imgThe African Union blasted the world’s only permanent war crimes court on Wednesday for its unrelenting focus on the continent, as it called for a case against Kenya’s deputy president to be dropped.“We have arrived at the conclusion that the International Criminal Court, whose establishment was strongly supported by Africa… is no longer a court for all,” Ethiopian Foreign Minister Tedros Adhanom Ghebreyesus said.The Ethiopian minister was speaking on behalf of the AU at the 14th session of the Assembly of States Parties, an annual meeting between the 123 countries that have signed up to the Hague-based ICC’s founding statute.The AU, led in particular by Kenya, has accused the court of unfairly targeting Africans for prosecution as the majority of its cases come from the continent.This included a failed case to try Kenyan President Uhuru Kenyatta and a faltering case against his deputy William Ruto, for allegedly masterminding deadly post-election violence in the east African country in 2007-2008 in which some 1 200 people died.last_img read more

Eagles 4-Way Track Meet Results

first_imgHigh Jump  Varsity – Finals x 4.12Kayla Bowling13’0 SRJac-Cen-Del 2.12Kayla Bowling13.9h SRJac-Cen-Del 1.10Elyse Hunger14:03h SRJac-Cen-Del 4×100 Relay  Varsity – Finals x 4.9Sophanna Decory21.0h PRJac-Cen-Del 1.12Rosie Newhart33’3Jac-Cen-Del 1600 Meters  Varsity – Finals x 2.9Sophanna Decory1:10h PRJac-Cen-Del 4×400 Relay  Varsity – Finals x Shot Put – 4kg  Varsity – Finals x Long Jump  Varsity – Finals x 5.9Madison Potts4’0Jac-Cen-Del 2.12Liberiti Stenger13’8Jac-Cen-Del 2.Shianna BellinghamKerigan FosterMadison PottsSophanna Decory4:53hJac-Cen-Del JCD Varsity track hosted a 4 way meet with Trinity Lutheran, Oldenburg and South Decatur.Girls: Oldenburg 88, JCD 74, South Decatur 30 and Trinity 15.Boys: Oldenburg 81, Trinity 46, South Decatur 42 and JCD 40.Courtesy of Eagles Coach Larry Hammond.JCD Results.100 Meters  Varsity – Finals x2.10Adrian Peetz12.0hJac-Cen-Del4.9Tanner Dilk12.6hJac-Cen-Del200 Meters  Varsity – Finals x5.9Tanner Dilk25.7hJac-Cen-Del400 Meters  Varsity – Finals x4.11Quentin Comer59.6h SRJac-Cen-Del3200 Meters  Varsity – Finals x5.10Nathan Laswell13:58h PRJac-Cen-Del4×100 Relay  Varsity – Finals x1.Tanner DilkMoritz WiesmuellerBlake SimonAdrian Peetz48.2hJac-Cen-Del4×400 Relay  Varsity – Finals x4.Adrian PeetzQuentin ComerMoritz WiesmuellerTanner Dilk4:02hJac-Cen-Del4×800 Relay  Varsity – Finals x3.Spenser JohnsonWilliam MeadorJarod WestonAustin Biddinger10:44hJac-Cen-DelShot Put – 12lb  Varsity – Finals x1.11Dylan Parcell39’2Jac-Cen-Del3.11Michael Schmitt37’0 PRJac-Cen-Del5.12Chris Douglas35’5Jac-Cen-DelDiscus – 1.6kg  Varsity – Finals x3.11Michael Schmitt109’4 PRJac-Cen-DelHigh Jump  Varsity – Finals x2.10Garrett Boor5’10Jac-Cen-Del4.10Blake Simon5’8 PRJac-Cen-DelLong Jump  Varsity – Finals x3.10Adrian Peetz17’1Jac-Cen-Del 3200 Meters  Varsity – Finals x 100 Meters  Varsity – Finals x 2.10Kelsey Sebastian78’1 PRJac-Cen-Del 3.Maria PurdyKerigan FosterLiberiti StengerKayla Bowling51.2hJac-Cen-Del 3.10Kelsey Sebastian26’9 SRJac-Cen-Del 4.10Taylor Wilhoit4’4Jac-Cen-Del 4×800 Relay  Varsity – Finals x 2.Madison PottsAutumn HammondKatie MinchOliva Wagner12:47hJac-Cen-Del 100m Hurdles – 33″  Varsity – Finals x 4.11Shianna Bellingham2:59h SRJac-Cen-Del 2.10Elizabeth Newhart28’3Jac-Cen-Del 2.12Kayla Bowling54.3h PRJac-Cen-Del 1.12Rosie Newhart88’7Jac-Cen-Del 800 Meters  Varsity – Finals x 3.11Shianna Bellingham6:06h SRJac-Cen-Del 3.10Elizabeth Newhart75’1Jac-Cen-Del 4.10Elyse Hunger6:17hJac-Cen-Del 5.9Katie Minch17:00hJac-Cen-Del 400 Meters  Varsity – Finals x Discus – 1kg  Varsity – Finals x 300m Hurdles – 30″  Varsity – Finals x 5.12Liberiti Stenger21.4h SRJac-Cen-Del 5.11Bruna Kapps Kronemburg4.0 PRJac-Cen-Dellast_img read more

Swansea reported over Vorm deal

first_img Vorm moved from the Liberty Stadium to White Hart Lane last month for an undisclosed fee, with Utrecht claiming they have not received 30 per cent of Vorm’s transfer fee, which they allege was part of a sell-on agreement between them and the Swans when he moved to Wales for £1.5million in 2011. A FIFA spokesperson said: “We can confirm that we’ve received a complaint from the club FC Utrecht against the club Swansea City in connection with the transfer of the player Michel Vorm. FIFA has received a complaint from Michel Vorm’s former club FC Utrecht in relation to the Dutch goalkeeper’s transfer to Tottenham from Swansea. Press Associationcenter_img “At this stage we cannot make any further comment.” Swansea last week issued a statement to say the transfer was “conducted and concluded correctly under Premier League rules”. A Swansea spokesman said: “It was approved by the Premier League and also FIFA via their TMS (Transfer Matching) system. “While we have been in contact with Utrecht as a matter of courtesy, we will continue to conduct our business in the best interest of our football club and our supporters, and not based on the views of other clubs.” last_img read more

Cricket News Virat Kohli achieves yet another feat in T20 International Cricket

first_imgNew Delhi : The Indian skipper Virat Kohli registered yet another feat in the first of two match T20 International series against Australia after being able to become the first player to score over 500 runs against an opponent in T20I cricket. He has amassed 512 runs against Australia in this format so far.In this innings, Kohli came to bat after India lost Rohit Sharma for five runs. The team was looking for a solid partnership and one will have to say that KL Rahul and Virat Kohli did just that, managing to register a partnership of 55 runs. Post this, Kohli departed for 24 runs off 17 deliveries. His innings was laced with 3 boundaries. However, he tried to go down the ground to Adam Zampa and mistimed the shot which went straight in the hands of Nath Coulter Nile.At the end of India’s innings, it wouldn’t be wrong to say that the men-in-yellow came with a proper plan to give India a tough time in the middle. Except for Rahul’s quick-fire 50, India doesn’t have much to be proud of. Having scored 126 runs in their quota of 20 overs, it will be interesting to see bowlers manage to replicate Aussie’s thoughts. HIGHLIGHTSVirat Kohli becomes the first player to score 500 plus runs against Australia in T20 cricket. KL Rahul registered his fifth T20 fifty. Australia restricts India to a below-par total. For all the Latest Sports News News, Cricket News News, Download News Nation Android and iOS Mobile Apps.last_img read more

Fakhar, Amir sparkle as Pakistan crush India to lift Champions Trophy

first_imgBy Ed OsmondLONDON,(Reuters)-Fakhar Zaman and Mohammad Amir shone as Pakistan defied the odds to overwhelm arch-rivals India by 180 runs and pull off a major upset in the Champions Trophy final at The Oval on Sunday.Fakhar capitalised on a lucky escape to strike a superb 114 and lift Pakistan to a commanding total of 338 for four and fast bowler Amir ripped out India’s top three batsmen before the defending champions subsided to 158 all out.Pakistan had come into the tournament as the lowest-ranked team and lost heavily to India in their opening group match but they beat South Africa and Sri Lanka to make the semi-finals where they knocked out hosts England.“Fakhar is a great impact player, he played like a champion batsman today,” Pakistan captain Sarfraz Ahmed said at the presentation ceremony.“Amir bowled brilliantly today but all my bowlers bowled really well. We have a young team and credit to my boys.”After India had won the toss, Fakhar, on three, was caught by wicketkeeper Mahendra Singh Dhoni off a Jasprit Bumrah no-ball and the 27-year-old left-hander took full advantage to make his first international century.He shared a fluent century opening partnership with Azhar Ali (59), the pair unleashing a barrage of crisp attacking strokes all around a sun-kissed ground.Azhar also continued his fine form, reaching fifty off 61 balls before he was run out following a mix-up with his partner.Fakhar lofted Ravindra Jadeja over long-on for six and got to three figures by sweeping Ravichandran Ashwin to the boundary.He celebrated with an extravagant twirl of his bat and kissed the turf as the Pakistan supporters sensed an unlikely win.Fakhar hit 12 fours and three sixes before skying a catch off Hardik Pandya but Pakistan had the perfect platform to make the highest total in a Champions Trophy final.THREE SIXESBabar Azam chipped in with a solid 46 and Mohammad Hafeez struck three sixes in a punchy unbeaten 57 that left India needing to produce the highest successful run chase in the tournament’s history to lift the trophy for the third time.Within three overs, however, their reply was in tatters as Amir produced a devastating spell of bowling.He trapped Rohit Sharma lbw for nought with a swinging delivery and removed India talisman Virat Kohli with another fine ball which the captain could only edge to point for five.Kohli, the world’s top-ranked one-day batsman, had been dropped off the previous delivery in the slips and the India fans looked shell-shocked as he trudged off.Their hopes now rested largely on the shoulders of Shikhar Dhawan who had been in fine form in the tournament but he made only 21 before nicking the inspired Amir to wicketkeeper Sarfraz.Spinner Shadab Khan snared Yuvraj Singh lbw for 22 and Dhoni, India’s former captain who has saved the team on many occasions, pulled Hasan Ali to Imad Wasim at deep square leg to depart for four.Shadab picked up his second wicket when Kedar Jadhav, on nine, gave Sarfraz a simple catch and India appeared to be crumbling meekly at 72 for six.Pandya, however, briefly raised their spirits with a quickfire 76, reaching his fifty with three successive sixes off Shadab and hitting six maximums in all before he was run out.Jadeja nicked Junaid Khan to slip for 15, Hasan had Ashwin caught by Sarfraz and Hasan forced Bumrah to lob another catch to the wicketkeeper, who pouched it gleefully to complete Pakistan’s first Champions Trophy win with 19.3 overs to spare.“Early wickets are never good, especially in a chase. We thought one big partnership would have set it up nicely,” Kohli said.“Pakistan had to earn their win and they made us make mistakes. We have no hesitation or shame to admit we didn’t play our best game today.”last_img read more

GOtv Boxing Night 20: Scorpion Eyes N1m Best Boxer Prize

first_imgNational super featherweight champion and knockout specialist, Ridwan “Scorpion” Oyekola, declared his intention to claim the N1million cash prize for the best boxer at GOtv Boxing Night 20 holding on Saturday at the Tafawa Balewa Square, Lagos. The prize is attached to the Mojisola Ogunsanya Memorial Trophy for the best boxer.Scorpion, who is billed to face Sikiru “Omo Iya Eleja” Shogbesan, a corps member, in a challenge duel, said he intends announce his qualities to the whole of Africa through the fight and walk away with cash prize. Scoprion, who won the prize at GOtv Boxing Night 15 and emerged runner-up at GOtv Boxing 13, said he is confident of winning again.“I won it once and came second once. This time, I’m sure of winning. I have prepared well and Shogbesan will be in trouble. I know he is a graduate, who is participating in the national youth service programme, but boxing is not big grammar and on Staurday, he’d realise this,” Scorpion said. The bout is one of the nine scheduled for the event, which will be headlined by the World Boxing Federation (WBF) Intercontinental heavyweight title fight between Onoriode “Godzilla” Ehwariemi of Nigeria and Ariel “Chiquito” Baracamonte of Argentina.Three other title fights are slated for the night. They are the West African Boxing Union (WABU) lightweight title bout between defending champion, Nigeria’s Rilwan “Real One” Oladosu, and Erick Quarm of Ghana; the WABU welterweight title bout between the reigning champion, Nigeria’s Rilwan “Baby Face” Babatunde and Ghana’s Sanitor Agbenyo; and a national bantamweight title bout between Sadiq Adeleke and Opeyemi “Sense” Adeyemi.In other fights, Taiwo “Esepo” Agbaje will take on Olusegun Moses in a national featherweight challenge bout, with reigning national light heavyweight champion, Adewale “Masevex” Masebinu, taking on Olanrewaju Segun in a challenge duel. Alaba “Eylbow” Omotola and Bolaji “Fight to Finish” Abdullahi will go head-to-head in a national lightweight challenge, while Cynthia “Omo Bobby” Ogunsemilore will face Aminat Yekini in an all-female national super featherweight challenge bout.The event will also feature live musical performances from “Bolanle” crooner, Zlatan; “Up to something” singer, Mayorkun, and “Mercy of the Lord” performer, Oritsefemi.The best boxer at the show will win a cash prize of N1million alongside the Mojisola Ogunsanya Memorial Trophy.GOtv Boxing Night 20 will be beamed live on Africa’s biggest sport channel, SuperSport, in 47 African countries.Share this:FacebookRedditTwitterPrintPinterestEmailWhatsAppSkypeLinkedInTumblrPocketTelegramlast_img read more

Prof focuses on cancer prevention

first_imgThe New York Times best-selling author, featured TED speaker and one of the world’s leading cancer doctors and researchers are just a few of the ways to describe Dr. David Agus.A Trojan since 2009, Agus is the director of the USC Norris Westside Cancer Center, director of the Center for Applied Molecular Medicine, professor of medicine at the Keck School of Medicine and professor of engineering at the Viterbi School of Engineering. Though Agus is currently recognized as the authority on cancer research and treatment — having served as doctor for the likes of Steve Jobs, Lance Armstrong and Ted Kennedy — it was space exploration that inspired him to study science.“I grew up during the Space Age when there was a lot of competition between the U.S. and Russia, and after the Russians sent the Sputnik to space, the government embarked on a major science education initiative,” he said. “Thus at a young age I caught the ‘science bug’ and decided I wanted to pursue a career in medicine.”After graduating cum laude from Princeton University with a bachelor’s degree in molecular biology, Agus earned his M.D. from the University of Pennsylvania and did his residency at Johns Hopkins University.Agus said he decided to specialize in oncology because it allows him to directly apply what is done in the lab to the lives of real patients. According to Agus, the nature of his field forces him to be innovative, especially in treating late-stage cancer patients.“In this field, you are able to take risks,” Agus said.In addition to being a conventional doctor, Agus is on the front lines of developing ways to integrate technology into the fight against cancer. In 2006, he co-founded Navigenics, a company that provides people with their individual genetic information, allowing them to see their predispositions to certain diseases and to take appropriate preventative measures. He also founded, the Internet’s largest cancer resource and community.Agus is a firm believer that the fight against cancer must focus on prevention.“It must be a ‘ground up’ movement and start with individuals,” Agus said. “My book, The End of Illness, is an anthem of that.”In The End of Illness, which spent over a month as The New York Times No. 1 bestseller after its January release, Agus argues that the key to curing cancer is preventing it in the first place. According to Fortune magazine, Agus calls for a completely new approach to medicine.“I want doctors to treat toward health and not treat toward disease,” he said.Agus said some simple ways to prevent cancer and other diseases include taking baby aspirin every day, keeping consistently active by walking from place to place and keeping a regular meal schedule.“If you eat lunch at noon one day, but then 2 p.m. the next, your body releases stress hormones that make you up to 80 percent more likely to contract diabetes,” he said.Though Agus is an internationally recognized figure who has done extensive work with many organizations and institutions, he said the opportunities and resources afforded him at USC are perfect for his work.“I am all about the convergence of multiple sciences in developing technology for health care and USC is one of the only places where you can do that. The emphasis USC places on multi-disciplinary study and work is perfect for what I do,” Agus said. “USC was built on a long-term vision of changing the world and that’s what I’m about.”last_img read more

Christian awarded Pac-12 player of the week for USC

first_imgAfter helping the USC women’s tennis team topple rival UCLA with a 6-1 victory in the regular season finale on April 18, junior Kaitlyn Christian became the seventh Woman of Troy to be named Pac-12 player of the week this season.In the match, Christian started the day off against the formerly No. 7 Bruins with an 8-3 doubles win alongside sophomore Sabrina Santamaria over UCLA’s Pamela Montez and Skylar Morton.Strong finish · In USC’s regular-season finale against UCLA, Christian won both her singles and doubles matches despite battling the flu. – Ralf Cheung | Daily Trojan In singles play, Christian dropped her first set and fell behind 2-0 in the second set but rallied back and defeated No. 90 Kaitlyn Ray with a 2-6, 6-3, 6-4 comeback victory despite battling the stomach flu.The win was Christian’s eighth straight and improved her singles record to 21-6 overall and a perfect 8-0 in conference play. She has done the bulk of her damage from court five, where she is 6-0 in singles.Christian and Santamaria, ranked No. 2 in the nation in doubles, finished the season undefeated with a 13-0 record, all from court one. In the upcoming Pac-12 championships, the two look to defend their 2012 doubles title.The No. 5-ranked Women of Troy concluded the regular season 21-2 overall and 9-0 in the Pac-12. USC clinched the Pac-12 team title with the victory over UCLA, and the win marked the first time that USC took back-to-back wins over UCLA since 2006.Christian joins senior Danielle Lao, sophomores Gabriella DeSimone, Giuliana Olmos, Zoë Scandalis and Santamaria, and freshman Ellie Yates as Women of Troy who have been named Pac-12 players of the week this season.With the regular season finished and a 13-game win streak in place, the Women of Troy now shift their focus to individual play at the Pac-12 championships, which begin on Thursday and conclude on Sunday in Ojai, Calif.last_img read more